There has been suspicion that this paralysis may be related in some way to enterovirus D68, which has infected so many children across the country. So far all evidence is inconclusive.
Acute flaccid paralysis (AFP) of unknown cause in California
VIROLOGY BLOG - October 7, 2014
In February 2014 I wrote about children in California who developed a poliomyelitis-like paralysis, also called acute flaccid paralysis or AFP.
| Enterovirus A71 can cause AFP |
However, the cause of this paralysis was not known. The CDC has released its study of these cases and concludes “The etiology of AFP with anterior myelitis in the cases described in this report remains undetermined.” (Etiology = The branch of medicine that deals with the causes or origins of disease.)
A total of 23 cases of AFP* in California were reported to CDC during the period June 2012 through June 2014. These cases were from diverse geographic regions of the state.
Specimens from 19 of the patients were available and tested for poliovirus, aroboviruses, herpesviruses, parechoviruses, adenoviruses, rabies virus, influenza virus, metapneumovirus, respiratory syncytial virus, parainfluenza viruses, Mycoplasma pneumoniae, Rickettsia, and amoebas.
Rhinovirus was detected in one patient, and enterovirus D68 in two patients; all others were negative for potential etiologic agents. All 23 patients with AFP also had anterior myelitis, inflammation of the grey matter of the spinal cord, which is characteristic of poliomyelitis.